Methylprednisolone is sodium methylprednisolone succinate for injection, sodium methylprednisolone succinate for injection and dexamethasone are common glucocorticoid drugs, the main difference between sodium methylprednisolone succinate for injection and dexamethasone is the different duration of the drug’s efficacy, the different duration of the side effects, and the different strength of anti-inflammatory effects. 1. The pharmacological effect time of the drug is different: Dexamethasone is a long-acting glucocorticoid, and Methylprednisolone Sodium Succinate for Injection is a medium-acting glucocorticoid, therefore, Methylprednisolone Sodium Succinate for Injection has a shorter pharmacological effect time on the organism than Dexamethasone. 2. The time of side effects is different: because dexamethasone acts on the human body for a longer period of time, and sodium methylprednisolone succinate for injection acts on the human body for a shorter period of time, therefore, the time of side effects of dexamethasone is slower, while the time of side effects of sodium methylprednisolone succinate for injection is faster. 3. anti-inflammatory effect strength is different: glucocorticoid drugs themselves have a strong anti-inflammatory effect, the anti-inflammatory effect strength of dexamethasone is about 6 times the strength of the anti-inflammatory effect of injection methylprednisolone sodium succinate. Note that the use of injectable methylprednisolone sodium succinate or dexamethasone can cause a variety of adverse reactions, need to be used under the guidance of a doctor, avoid unauthorized use.