Adrenal gland has no function here may refer to the primary chronic adrenal hypofunction, the treatment includes basic treatment, etiologic treatment, treatment of adrenal crisis, etc. It is recommended to follow the doctor’s instructions for treatment. 1. Basic treatment: glucocorticoid replacement therapy can be used, and a basic amount is determined according to the patient’s height, age, weight, etc. Hydrocortisone is usually used; salt should be supplemented, and hydrocorticosteroid therapy should be performed. Salt should be supplemented with 8-10 grams of salt per day, and salt intake needs to be increased in the case of accompanying diarrhea or profuse sweating, etc. Oral treatment with 9alpha-fluoro-cortisone can be performed as well. 2. Treatment of the cause: active tuberculosis requires anti-tuberculosis treatment, such as the use of isoniazid, rifampicin and so on. If it is caused by autoimmune disease, it should also determine whether there is other glandular hypoplasia, and treat accordingly. 3. Treatment of adrenal crisis: rapid use of saline for rehydration therapy, appropriate glucose supplementation to avoid hypoglycemia, intravenous hydrocortisone therapy. When primary chronic adrenocortical hypoplasia occurs, it is recommended to cooperate with doctors for active treatment.