Lip blistering is a clear fluid-filled mucosal protrusion that occurs on the mucous membrane of the lips. This lesion is very common. When these small lip glands are damaged, the saliva flows out to the submucosa, forming a small bladder-like blister, which is called a “mucous cyst” in dentistry. Therefore, lip biting is the most common cause of lip blisters. Some patients have uneven teeth, and the tips of the teeth often stimulate the local lip mucosa, which may also form small bubbles on the lips. These small mucous cysts are not serious, but they do not disappear on their own, often deflate after the saliva flows out after breaking, and gradually increase in size after the mucosa heals. Therefore, the best way is to have the cysts removed by an oral surgeon under local anesthesia, which is minimally invasive and does not affect the appearance. After surgery, care should be taken not to eat hot food to stimulate bleeding and to avoid eating hard food to pinch the wound, waiting for a week or so for the mucosa to heal. Patients with this problem should quit the bad habit of biting their lips to avoid the emergence of new mucous cysts. Therefore, there is no need to panic about lip blisters, and it is recommended to visit the oral surgery department at a later date for consultation and treatment.