Calf pain may be caused by physiological factors such as prolonged running or heavy physical labor, or it may be caused by pathological factors such as trauma, osteoporosis and lumbar disc herniation. 1. Physiological factors: prolonged running or heavy physical labor can lead to muscle fatigue, a large amount of lactic acid accumulation and slow metabolism, which can cause calf pain and soreness, which can be gradually relieved with proper rest. 2. Osteoporosis: Mostly seen in the elderly, rapid calcium loss or insufficient calcium intake can lead to osteoporosis, which can be manifested as pain in the lower back and limb pain and weakness. 3. Lumbar intervertebral disc herniation: Degenerative lesions of the lumbar spine can lead to herniation of the intervertebral discs, and the nerve root is compressed, which can cause the symptoms of nerve compression in the lower limbs, and the symptoms of soreness and numbness of the lower legs, accompanied by pain in the lumbar vertebrae and the buttocks. There are many other causes of calf pain, if the patient’s calf pain symptoms continue to be unrelieved, it is recommended to consult the hospital as soon as possible, after clarifying the cause of the disease for standardized treatment.