Patients with novel coronaviruses may develop secondary infections after cure. Novel coronaviruses are usually highly contagious and can be spread by airborne droplets and direct contact. When a patient with novel coronavirus infection is cured, the body produces antibodies to the novel coronavirus, which have an immunoprotective effect on the body. If the new coronavirus has mutated, the body’s own immunity will not be able to resist the virus and secondary infection may occur. After recovery, if you are overworked or stay up too late, your immune system will be weakened, and if you do not protect yourself properly, frequent close contact with people infected with the new coronavirus may also lead to secondary infection with the new coronavirus. Therefore, people infected with the new coronavirus should not take it lightly even after they have been cured, and need to strengthen their protection by wearing masks when going out, avoiding going to the infected area and its surrounding places, maintaining good living habits, and strengthening their own immunity.