Because children’s thermoregulatory function is poor, and easily infected by a variety of external pathogens, so children’s colds will appear first fever and then runny nose. Children’s upper respiratory tract infections are usually caused by invasion of bacteria, viruses and other pathogens, which in turn will stimulate the children’s body immune cells to release interleukins, due to the children’s poor thermoregulatory function, cytokines into the blood circulation may lead to thermoregulatory centers to be affected, and therefore fever symptoms will occur. With the further development of inflammation, the child will have a runny nose and other symptoms. If a child has fever and runny nose, it is recommended to consult a doctor in time, under the guidance of the doctor, improve the relevant examination, clarify the cause of the disease, and target treatment.