Bed rest should be provided within 24 hours after renal puncture biopsy, and turning exercises can be performed with the help of family members or caregivers between 6 and 24 hours after the procedure to improve patient comfort. However, it should be noted that the patient’s voluntary force should be avoided when turning over. If there is no discomfort 24 hours after the operation, the patient can get out of bed to take care of their own activities, such as going to the toilet, washing up, etc., but no strenuous activities. Renal puncture biopsy is an invasive examination of the kidneys, and almost all patients will have microscopic hematuria after the operation, and some patients may have carnal hematuria. Therefore, it is important to reduce activities after the procedure to avoid bleeding and hematoma formation, etc. In addition, patients after renal puncture biopsy should increase the amount of drinking water to flush the urinary tract to prevent clots from blocking the urinary tract and complicating urinary tract infection, and drink water in a small amount of multiple times. If the patient is accompanied by edema, decreased urine output and other symptoms, the amount of water consumption should be decided under the guidance of the doctor. It is recommended that the patient under the guidance of a professional doctor to carry out renal puncture biopsy, after the operation, if there is any discomfort, inform the doctor in time, and follow the doctor’s instructions for treatment.