Cold is a common disease, common symptoms include: nasal congestion, runny nose, sore throat, cough, etc. In severe cases, fever and general joint and muscle pain can occur. Medication is the common preferred method, but due to the lack of medical knowledge, people often choose the wrong medication, or because of improper medication, causing unnecessary adverse drug reactions, the following talk about a variety of different people with colds medication. Children’s colds Infants and young children with colds, do not use drugs containing caffeine and pseudoephedrine, because these drugs have a central excitatory effect, such as: Crypto, new Parc, day and night Benadryl, compound aspirin tablets, etc.. At the same time, we should adjust the drug dose dosage according to the age, height and weight of children, and not give adult doses, which can cause poisoning. It should also be noted that children under 12 years of age are prohibited from cold medicines containing aspirin ingredients such as compound aspirin tablets, because such drugs can cause Rey Syndrome [encephalopathy fatty liver syndrome], which is an acute progressive encephalopathy. The pathology is characterized by acute cerebral edema and steatosis of the liver, kidneys, pancreas, heart muscle and other organs. The main ultrastructural alterations are mitochondrial abnormalities. Clinical features are the development of cerebral symptoms such as vomiting, impaired consciousness and convulsions as well as abnormal liver function and metabolic disturbances after a prodromal viral infection. Cold and Flu in Pregnant Women Some drugs such as Neupalco, Day & Night Pepcid, White Plus Black, Crypto, Compound Aspirin Tablets and other cold and flu drugs contain aspirin, ibuprofen, diclofenac and other ingredients that can cause prolonged pregnancy when taken by pregnant women. Some medications such as Baijiahei Night Tablets, Crypto, Sensac, Teck, and compound aspirin tablets contain aspirin, benadryl, and amantadine, which may cause fetal malformation when taken by pregnant women. Therefore, if the cold medicine contains indomethacin, aspirin, diclofenac, ibuprofen, codeine, dextromethorphan, amantadine and other ingredients, it is prohibited to be taken by pregnant women. Pregnant women need to be cautious when taking medicines containing aminophenazone, acetaminophen, pseudoephedrine, diphenhydramine, chlorpheniramine, terfenadine, etc. It is best to apply them under the guidance of a doctor. For breastfeeding women, the main concern of cold medication for breastfeeding women is whether the medication will affect the newborn and inhibit lactation, so if the medication contains ingredients such as benadryl, indomethacin, chlorpheniramine, amantadine, etc., it is prohibited for pregnant women. Of course, if the drug contains acetaminophen, aspirin, pseudoephedrine, diphenhydramine, chlorpheniramine, terfenadine, codeine, caffeine, etc., it should still be used with caution. For patients with cardiovascular diseases, attention should be paid to whether the cold medication can cause an increase in blood pressure, aggravate myocardial ischemia and other adverse reactions, such as neo-control, silver Delfin contains pseudoephedrine, hypertensive patients taking it can cause increased blood pressure, increased heart rate, increased myocardial ischemia; some drugs contain terfenadine, patients taking it can cause Q-T interval prolongation and other cardiac arrhythmias, etc. Some drugs contain terfenadine, which can cause arrhythmia such as Q-T interval prolongation. Some patients with hypertension and stroke usually take some aspirin, and if they take cold drugs containing aspirin, it may strengthen the anticoagulant effect and cause bleeding tendency or hemorrhage. For cardiovascular patients, it should be noted that drugs containing indomethacin are prohibited for severe heart failure, and drugs containing pseudoephedrine are prohibited for severe hypertensive cardiac insufficiency. For patients with respiratory diseases, a cold can cause further aggravation of the original disease, inducing acute exacerbation of asthma, chronic obstructive pulmonary disease and pulmonary heart disease. Therefore, bronchial asthma patients should prohibit or cautiously use cold medicines containing aspirin, ibuprofen, acetaminophen and other ingredients, such as compound aspirin, day and night pepcid, and crack. For patients with chronic obstructive pulmonary disease, coughing more sputum should be cautious to use cold medicines containing central cough suppressant ingredients codeine, dextromethorphan, also not beneficial to take drugs containing chlorpheniramine, diphenhydramine and other drugs that can easily cause dry sputum. Peptic ulcer patients with colds Some cold medications contain aspirin, indomethacin, ibuprofen, diclofenac and other ingredients, these drugs often cause duodenal or gastric ulcers or make them worse, so they should be prohibited or used with caution. For pyloric ulcer patients, use Benadryl and Chlorpheniramine with caution, as these drugs can aggravate pyloric obstruction.