Vulvar itching is a very annoying and stubborn symptom, mostly paroxysmal, sometimes good and sometimes bad, and often caused by a variety of reasons. The most common cause is a combination of infections of the genital tract, such as trichomonas vaginalis, fungus, or bacterial vaginosis. Some vulvar itching is not caused by bacteria, but may be caused by systemic or local factors, such as combined vulvar neurodermatitis, external sclerosing lichen planus, etc. Patients can have severe vulvar itching, and for vulvar itching where the cause cannot be found, it may be caused by a decrease in estrogen levels in menopausal women. Menopause is a period when women change from a period of reproductive vigor to old age, and the level of estrogen in the body gradually decreases. Due to the lack of estrogen stimulation, the vulva and vaginal tissues shrink, the vaginal walls become thinner and drier, the mucosal folds disappear, the vagina becomes shorter and narrower, and the elasticity of the vaginal walls decreases. As a result, patients experience discomfort such as itching, irritation, burning and vaginal dryness of the vulva. Sexual intercourse may lead to tissue laceration and ulceration with spotting and bleeding. In addition, the uterus and ovaries gradually shrink. However, these symptoms may take several years to manifest themselves. Therefore, for patients with vulvovaginal itching during menopause, we first need to perform a general physical examination and gynecological examination, out of systemic diseases, such as is there a combination of diabetes mellitus? Are there any specific infections of the reproductive tract? Is there a combination of sex hormone use? If there is no obvious abnormality in the physical examination, and there is obvious atrophy of the genital tract, i.e. atrophy of the vulvar skin, thinning of the subcutaneous fat, and combined with other parts of the body, both can be considered as having senile vulvar itching. General treatment includes prohibiting irritating drugs or solutions to scrub the vulva or sitz bath, avoiding scratching the affected area with hands or instruments, applying anti-itch creams and cod liver oil ointment for local treatment, and recommending the use of estrogen ointment, such as estriol ointment (Ovitin) and combined estrogen ointment (Bemeli ointment), under the guidance of a doctor, which can significantly relieve vulvovaginal dryness and itching in middle-aged and elderly women and relieve It can also relieve and treat symptoms such as frequent urination, urinary urgency and recurrent urinary tract infections in middle-aged and elderly women. If these patients have menopausal symptoms such as hot flashes and sweating, they can also be treated with oral estrogen, which can not only treat systemic symptoms but also relieve local vaginal symptoms.