Iodine oil is not recommended for hysterosalpingography for the following reasons: 1. If the contrast agent reverses into the vein during the imaging procedure, iodine oil pulmonary embolism may occur; 2. Iodine oil can cause granuloma and is difficult to absorb in the abdominal cavity. 3. Iodine oil is highly viscous and painful for imaging. In view of the above understanding, I do not recommend the use of iodine oil. Now iodine oil has been eliminated. Aqueous iodine agents include ionic and non-ionic types such as compounded pantethine glucosamine, iopidol, etc. The contrast agent applied in hysterosalpingography flows into the pelvic cavity in the natural lumen, not directly into the blood vessels, and has little effect on the kidneys and plasma osmolality. We generally use compounded pantethine glucosamine, which is cheap and practical, and side effects are rare. For patients with clinical requirements we can also use more advanced nonionic contrast agents such as iopidol. Aqueous contrast agents are usually completely metabolized in the body in 48 hours and have no effect on pregnancy.