The treatment of depression after stroke includes pharmacological and non-pharmacological treatments. Non-pharmacological treatments are cognitive therapy as well as psycho-psychological and behavioral therapies. Pharmacological treatment includes antidepressant medication, with both Chinese and Western medicine. Non-pharmacological treatment is mainly psychological and cognitive therapy, first of all, health education about stroke, so that patients have a correct understanding and a positive attitude, as the information about stroke is improved, or the correct understanding of the disease, depression symptoms will be alleviated. In addition to stroke health education, psychological counseling should be provided to the patient. In addition to health education about stroke, we should also provide psychological guidance to the patients, so that they can face the current stroke positively and have confidence that stroke is treatable, prognosis is good and preventable through the efforts of patients and medical staff. After the patient has confidence in the disease, the depressive symptoms will be relieved. The psycho-psychological support should also be provided, and this support includes explaining clearly that emotions, especially depression, have an impact on stroke, and that stroke can only be recovered if the emotions are good and the state of mind is good. If all these things are not completely well, some drug interventions should be taken. These drug interventions can be western or Chinese medicine, single or combined. But the medication should be used selectively with antidepressants, and the medication should be used with attention to their interactions to avoid their interactions.