Biopsies of gastric celiac disease are categorized into two outcomes, one benign and one malignant. If gastric celiac disease is subjected to gastroscopic pathological tissue biopsy, the results of the examination are benign or malignant, in most cases, they are benign, mostly suggesting local inflammatory changes, and in a few cases, they are malignant tumors, i.e. gastric cancer. If the pathological biopsy is benign, the main treatment is medication, which usually requires taking acid-suppressing drugs and gastric mucosa-protecting drugs as prescribed by doctor, such as omeprazole, rabeprazole, bismuth potassium citrate, thioglycollate and so on, which can reduce the secretion of gastric acid and promote the recovery of gastric mucosa. However, if the diagnosis is malignant, early surgical treatment is generally required. Some patients without surgical indications can be treated with chemotherapy and targeted drug therapy. Gastric celiac biopsy should be based on the results of the examination with the doctor active treatment to avoid aggravation of the condition.