Commonly used analgesics in clinical practice include NSAIDs, acetaminophen and opioid analgesics, all with different mechanisms of action.
NSAIDs (aspirin, ibuprofen, meloxicam, etc.) inhibit prostaglandins and reduce the production of inflammatory factors, thereby relieving pain symptoms. Oral use of newer drugs such as celecoxib for patients with pre-existing gastrointestinal disorders.
Acetaminophen relieves or treats low back pain by inhibiting prostaglandin synthesis within the centre and reducing inflammatory factor production.
Opioid analgesics relieve pain symptoms by blocking the binding of central neurotransmitters to receptors. Opioid doses used for analgesia are low and far from addictive, and such drugs are prescription drugs and must be prescribed by a clinician.
Therefore, all pain medications are not at risk of addiction if taken regularly by mouth as prescribed by a physician.
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