Metronidazole gel is not very effective in removing blackheads and acne. The main component of the drug is metronidazole, which is an antibiotic against anaerobic bacteria, protozoa and mites, and has a good effect on some inflammatory acne lesions. However, blackheads are mainly due to the narrow keratinization of the opening of the upper part of the sebaceous gland of the hair follicle, and the sebum contents are secreted more and cannot be discharged smoothly, so they are blocked in the mouth of the hair follicle and are locally oxidized and blackened to form blackheads. The main treatment is to use drugs that regulate follicle keratinization and inhibit sebum secretion, and the more commonly used ones are vitamin A acid preparations, such as Adapalene gel, which are more effective.
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