Psoriasis, also known as psoriasis, is an immune-mediated chronic, recurrent inflammatory skin disease induced by a combination of genetic and environmental effects. Suitable ointments should be selected according to the characteristics of skin lesions and patients’ needs, such as vitamin D3 derivatives (tacalcitol ointment), glucocorticosteroids (hydrocortisone butyrate cream), and calcium-modulated phosphatase inhibitors (tacrolimus ointment). 1. Vitamin D3 derivatives: tacalcitol ointment for psoriasis vulgaris, adverse reactions include itching, skin redness, irritation. Patients with a history of allergy to the components of this product are prohibited from using it. 2. Glucocorticoid: hydrocortisone butyrate cream, its topical use has anti-inflammatory, anti-allergic, anti-itching and reduce oozing effect. Adverse reactions: long-term use can lead to skin atrophy, capillary dilatation, hyperpigmentation and secondary infection. Occasionally allergic reactions. Contraindicated in infectious skin diseases. 3. Calcium-modulated phosphatase inhibitors: tacrolimus ointment, its adverse reactions to the skin burning sensation, itching and other symptoms. It is contraindicated in patients with a history of hypersensitivity to tacrolimus or any other component of the preparation. It is recommended that patients with psoriasis go to regular hospitals in a timely manner, standardize the use of medication under the guidance of the doctor, and avoid self-medication.