Chest tightness and back pain can be seen in heart disease, digestive disease, lung disease, etc., and need to be treated according to the disease. 1. Heart disease: coronary heart disease is common. Coronary heart disease will appear chest tightness, palpitation, panic, angina, back pain, can not lie down at night and other symptoms. Need oral nitroglycerin, metoprolol, statin and other drugs for treatment. 2. Digestive system diseases: such as gastritis, gastric ulcer, etc., often appearing symptoms such as loss of appetite, nausea and vomiting, epigastric pain, and also lead to chest tightness and back pain. Gastroscopy, ultrasound of the upper abdomen, CT of the upper abdomen and other tests are needed to clarify the condition and then take medication. Commonly used drugs include amoxicillin, omeprazole, aluminum phosphate gel and so on. 3. Thoracic and pulmonary diseases: pleural effusion, pleurisy, pneumonia and other thoracic and pulmonary diseases will appear chest tightness, chest pain, back pain, dyspnea, cough and other symptoms, you can use antibiotics such as ceftazidime, levofloxacin and other anti-infective treatment, rifampicin isoniazid and other anti-tuberculosis treatment, should also be used to use ibuprofen, aminoglossum, and other drugs for symptomatic treatment. The causes of chest tightness and back pain are many, which can lead to serious consequences, and need to go to the hospital in a timely manner, and simple drug treatment may not be able to cure the disease, we need to choose the most appropriate treatment program according to the patient’s condition.