Patients with symptoms of chest tightness, shortness of breath and panic, may be related to strenuous exercise, bad mood and other physiological factors, but also may be related to chronic bronchitis, coronary heart disease, heart failure and other pathological factors, the patient should consult a doctor in time for examination and symptomatic treatment. 1. Strenuous exercise: when the patient for a long time long-distance running, basketball and other strenuous activities, or engaged in heavy physical labor, easy to cause the body overload, may cause chest tightness, shortness of breath and panic symptoms. 2. Adverse emotions: common adverse emotions such as excitement, tension, anger, etc., when the patient is stimulated by adverse emotions, it may cause chest tightness, shortness of breath and panic. 3. Chronic bronchitis: it refers to the chronic non-specific inflammation of the trachea, bronchial mucosa and the surrounding tissues, and its main symptoms include coughing, coughing up sputum, wheezing, or shortness of breath, etc. When the patient coughs violently, it may cause the patient to have chest tightness, shortness of breath, and panic. 4. Coronary heart disease: it is caused by coronary atherosclerosis leading to myocardial ischemia and hypoxia, and its main symptoms are chest tightness and chest pain, shortness of breath, panic and other uncomfortable symptoms after activity, and myocardial infarction can occur in severe cases. 5. Heart failure: due to various diseases such as hypertension, coronary heart disease, pulmonary heart disease, etc. leading to a decline in cardiac function, the patient’s activities and even rest will appear chest tightness, shortness of breath, panic. In addition, cardiomyopathy, myocarditis, hyperthyroidism, anemia and other diseases may appear chest tightness, shortness of breath, panic and other discomforts, it is recommended that the patient consult a doctor in time, to clarify the cause of the disease, and active treatment.