Chest tightness, shortness of breath, back cold can be seen in angina pectoris, heart failure, reflux esophagitis, chronic obstructive pulmonary disease, bronchial asthma and other diseases. Chest tightness, shortness of breath and back cold are mostly seen in patients with angina pectoris, myocardial ischemia attack can appear chest tightness and shortness of breath, rather accompanied by back cold sweat and other manifestations. Patients with heart failure have pulmonary stasis, and symptoms of chest tightness and shortness of breath can also occur during an attack, and if accompanied by myocardial ischemia at the same time, symptoms of cold back can occur. Reflux esophagitis can irritate the esophagus, reflex symptoms of chest tightness and shortness of breath, and some patients’ symptoms can be reflected to the back, manifesting my back cold performance. Chronic Obstructive Pulmonary Disease (COPD) can lead to insufficient ventilation and oxygen deprivation in the body, which can be manifested as tightness in the chest, shortness of breath and coldness in the back. Bronchial asthma can lead to airway spasms, which can also lead to oxygen deprivation during exacerbations, manifesting as chest tightness, shortness of breath, and chills on the back. If the symptoms of chest tightness, shortness of breath and back cold are obvious, it is necessary to go to the hospital in time to improve the electrocardiogram, cardiac ultrasound, gastroscopy and other related examinations, so as to make a clear diagnosis and give treatment.