The presence of other allergic substances or the improper use of anti-allergy medications is often considered in drug allergies that have not been well for many days. It is necessary to conduct allergen screening, careful screening of daily contact items, and feedback to the doctor to adjust the medication. 1. The existence of other allergic substances: for long-term drug allergy has not improved the patient, it is recommended to carefully find the daily contact items, whether they still exist to other food or drug allergies, you can also go to the regular hospital to do allergen screening, to clarify the other foods or items that lead to their own allergies, and then avoid contact. 2. Inappropriate use of anti-allergy drugs: patients may have long-term drug resistance to a certain type of anti-allergy drugs, or the dosage and usage do not follow the instructions of the doctor, it is recommended to take anti-allergy drugs according to the instructions of the doctor, if according to the instructions of the doctor is still not effective, it is recommended to review, go to the regular hospital and ask the doctor to adjust the dosage and usage or change the anti-allergy drugs. If the drug allergy does not relieve for many days or there is a tendency to aggravate, it is recommended to go to the hospital in a timely manner, after clarifying the cause of the disease under the guidance of a doctor to standardize the treatment.