Ineffective heart failure medications can be considered as treatment options include: cardiac resynchronization therapy, implantation of cardioverter-defibrillator, surgical treatment of the primary disease, and cardiac transplantation.
1. Cardiac resynchronization therapy: some patients have atrial or ventricular contraction asynchrony, resulting in heart failure due to reduced myocardial contractility. When heart failure symptoms still exist after the use of optimal anti-heart failure medications, cardiac resynchronization therapy can be considered, which can effectively improve myocardial contraction, increase the volume of cardiac excretion, and alleviate the symptoms of heart failure.
2. Implantation of cardioverter-defibrillator: For refractory heart failure caused by persistent malignant ventricular arrhythmia, implantation of cardioverter-defibrillator (ICD) can be considered, which is effective in cardioverter-defibrillator to maintain hemodynamic stability.
3. Surgery for primary disease: For patients with clear primary disease and ineffective medical treatment, surgery can be considered for primary disease, such as ventricular septectomy for patients with hypertrophic cardiomyopathy, valve repair, plasty or replacement for patients with heart valve disease, and pericardiectomy for patients with constrictive pericarditis.
4. Heart transplantation: For patients with primary heart failure or organic lesions of the heart that are difficult to be repaired with ineffective medical treatment, heart transplantation can be performed, but it is difficult to perform the operation and the donor is difficult to be obtained, which can be considered by patients with the condition.
Heart failure patients with ineffective drug treatment are recommended to go to a specialized cardiology hospital as soon as possible, and ask a professional doctor to evaluate the condition and decide the specific treatment.