After mole spotting, you can use medicines to promote wound healing under doctor’s instruction, such as epidermal growth factor, fibroblast growth factor, etc., which can help wound healing; if the wound is infected, you can use antibiotic ointment such as mupirocin ointment and fusidic acid cream to fight infection according to doctor’s instruction. Mole spotting usually uses laser, freezing and other ways to remove epidermal moles, no matter which method is used, there will be trauma to the local area, and usually do not need topical medication, just need to keep the wound dry and clean. If you want the skin wound to heal faster after the operation, you can apply topical drugs to promote wound healing, such as fibroblast growth factor, epidermal growth factor, etc., which can promote wound healing and speed up the recovery of the wound. If there is infection after mole spotting, you can apply antibiotic ointment as prescribed by the doctor, such as mupirocin ointment, fusidic acid cream, etc., which has the effect of anti-infection; if the symptoms of infection are serious, you can also take sensitive antibiotics orally under the guidance of the doctor, such as cephalosporin antibiotics. Whether you need topical ointment after mole spotting, and which kind of ointment you need, the specific situation suggests consulting a professional doctor, and choosing a suitable ointment to apply under the doctor’s guidance. Patients should take good care of themselves after mole spotting, keep local cleanliness and hygiene, prevent infection, pay attention to nutritional balance in diet, pay attention to sun protection, etc., which is conducive to the recovery of the wound.