After drug treatment of chronic renal insufficiency, most of the indicators can be normalized, such as hyperkalemia, metabolic acidosis, etc., but blood creatinine, urea nitrogen generally can not reach normal, and the treatment drugs can not be discontinued arbitrarily because the disease can not be completely cured, the treatment is mainly aimed at slowing down the progression of the disease. Chronic renal insufficiency patients are often combined with renal function abnormalities, such as elevated blood creatinine, urea nitrogen, hyperuricemia (elevated blood uric acid), acidosis (decreased carbon dioxide binding capacity), calcium and phosphorus disorders (hypocalcemia, hyperphosphatemia), anemia (lowered hemoglobin), hyperkalemia (increased potassium) and other indicators of abnormality. Clinical treatment for the above conditions can choose renal failure, febuxostat, sodium bicarbonate, calcium acetate, lanthanum carbonate, roxarestat, calcium polystyrene sulfonate and other drugs, most of which can reach the normal level, but the blood creatinine and urea nitrogen can not be restored to normal in general. Even if the above indicators are normalized, it is still necessary to insist on taking the medication and adjust the usage and dosage of the medication according to the doctor’s prescription. The above medications should be used in accordance with the doctor’s prescription, and should not be used without authorization. Patients with chronic renal insufficiency are advised to consult regular hospitals in time, complete the relevant examinations, and carry out targeted treatment according to the situation.