Drug-induced renal injury, the emergence of urinary oliguria should promptly stop the use of suspected drugs, and the use of furosemide, glucocorticoids, immunosuppressants and other medications; meet the indications of the feasibility of hemodialysis treatment. 1. Stop drug: stop the use of suspected drugs in time to avoid further aggravation of renal injury. 2. Drug treatment: drug-induced renal damage can be treated with glucocorticoid drugs such as methylprednisolone and immunosuppressants according to the situation to inhibit immune reaction and reduce renal damage. Meanwhile, furosemide and sodium bicarbonate can be used to maintain water and electrolyte balance. 3. Hemodialysis: patients with drug-induced renal injury with low urine, obvious edema, accompanied by creatinine, urea nitrogen increase, meet the indications, should be timely hemodialysis treatment. Drug-induced renal injury, the emergence of oliguria, should go to the hospital in a timely manner, under the guidance of the doctor to standardize the treatment, to avoid further aggravation of the condition.