There is no topical ointment that can cure spider nevus. Spider nevus is a symptom, and there are many causes for this symptom, which can be divided into physiological and pathological causes: spider nevus caused by physiological causes usually does not need treatment, while spider nevus caused by pathological causes should be actively treated for the primary disease, and be improved by physical therapy, surgery, and so on. 1. Physiological causes: mostly seen in adolescent females, pregnant women, etc. Usually, it does not need treatment and can subside on its own; if it affects the aesthetics, it can be treated with laser therapy, microwave therapy, surgery, etc. under the guidance of doctors to improve the symptoms. 2. Pathological causes: commonly found in liver cirrhosis and other diseases, when liver function is abnormal, it will affect the inactivation of estrogen in the body, which will lead to the occurrence of spider nevus, patients need to comply with the doctor’s instruction to actively treat the liver disease, and those who have the demand for the treatment of spider nevus can improve it through carbon dioxide laser, high-frequency electrocautery and other physical treatment measures. It is recommended that patients with spider nevus should go to regular hospitals for timely examination, follow the doctor’s instructions after a clear diagnosis, and avoid abusing medication by themselves.