Photodynamic therapy for warts is more effective. Condyloma acuminatum is a skin growth in the genital area caused by human papilloma virus infection. The principle of photodynamic therapy is that photosensitizers gather in the lesion tissue and are subsequently excited by specific wavelengths of light irradiation, which generates singlet oxygen or free radicals, resulting in necrosis of the lesion tissue, with little damage to normal tissue. Adverse reactions include localized burning sensation, erythema, and pain. Photodynamic therapy is suitable for smaller warts, urethral condyloma acuminatum, and the prevention of recurrence treatment after taking medication and physical therapy to remove warts. The actual warts should be examined in a regular hospital, and the specific treatment measures should be decided in accordance with the doctor’s instructions.