Dapoxetine hydrochloride can be used to treat premature ejaculation and generally works. Premature ejaculation is defined as poor ejaculatory control, where ejaculation occurs before, during, or shortly after insertion of the penis into the vagina, or before full erection. Dapoxetine is a potent pentazocine reuptake inhibitor that can be used to treat premature ejaculation in men. In general, the drug still works well for patients with simple premature ejaculation. Common adverse reactions to Dapoxetine include headache, dizziness, nausea, and diarrhea, etc. These adverse reactions are usually transient and resolve quickly. It should be noted that Dapoxetine is forbidden to be used in patients who are allergic to the drug components, patients with organic heart disease, patients with moderate to severe liver damage, and also can not be used in combination with ketoconazole, itraconazole, ritonavir and other powerful cytochrome P4503A4 inhibitors. When using medication, it is important to follow the doctor’s instructions, rational application of drugs, do not use drugs arbitrarily, to avoid causing serious adverse reactions.