Cuttlebone can be used to treat premature ejaculation caused by kidney yang deficiency (lack of yang energy in the kidneys), but there is no clinical “cure for premature ejaculation”. Cuttlebone is the dried oocyte sheath of the mantis family insects, such as the big knife mantis, small knife mantis or giant axe mantis. This medicine is sweet and salty and flat, belonging to the liver, kidney meridian, has the effect of fixing semen and shrinking urine (consolidate semen and urine, preventing random leakage), tonifying the kidney and helping yang. It can be used in the treatment of seminal emission and slippery semen, frequent urination, and white urine (cloudy urine like white slurry). The adverse effects of the drug are not clear, but greasy and spicy food should not be taken while taking it. As the drug has the effect of tonifying the kidney and helping the yang, according to the theory of traditional Chinese medicine for premature ejaculation caused by insufficient kidney yang, the drug can be used for treatment under normal circumstances. Patients with premature ejaculation are advised to go to a regular hospital for treatment under the guidance of a professional physician.