The clinical reason why patients with burns are prone to infection is due to the loss of the barrier function of the skin mucosa, which normally does not cause skin mucosa infections in normal people because the normal skin mucosa has a barrier function and has a defensive effect against common bacteria. However, when the skin mucosa is damaged during burns, it can cause secondary infection by parasitic bacteria, such as the common bacteria of the skin mucosa, Staphylococcus aureus, Staphylococcus epidermidis, in addition to Gram-negative bacilli can cause infection. Mild cases may cause localized skin and soft tissue infections, which are usually clinically possible with a simple change of medication. However, in severe cases, bacteria may enter the bloodstream, leading to sepsis, which is more critical. If antibiotics are not actively applied, severe infections may occur, resulting in infectious shock and multiple organ failure, leading to death. Therefore, patients with burns must pay attention to local medication changes and actively apply anti-inflammatory drugs to treat those with a more pronounced propensity for infection.