What is a safe dose of propylthiouracil for pregnant women with hyperthyroidism?

Under normal circumstances, pregnant women suffering from hyperthyroidism are advised to use propylthiouracil with caution, and if used, it should be used under the guidance of a doctor, usually 50~300mg, with the specific dose determined by an endocrine specialist after assessing the condition. Propylthiouracil is an antithyroid drug, and its mechanism of action is to prevent the iodination of tyrosine and the condensation of iodinated tyrosine in the thyroid gland through the inhibition of the peroxidase enzyme in the thyroid gland, thus inhibiting the synthesis of thyroxine. When using propylthiouracil, it should be noted that the use of propylthiouracil is prohibited for those who are allergic to the product, those with severe hepatic impairment, and those with severe leukocyte deficiency. And patients may experience adverse reactions such as headache, dizziness and arthralgia after use. It is recommended that when a pregnant woman suffers from hyperthyroidism, she should be treated under the guidance of a doctor in a timely manner, and the dosage of drugs in drug treatment should be in accordance with the doctor’s instructions, do not use drugs and adjust the dosage of drugs without authorization, so as to avoid delaying the condition.