Several common medicines for the treatment of premature ejaculation are selective 5 hydroxytryptamine reuptake inhibitors, local anesthesia drugs and so on. 1. Selective 5 hydroxytryptamine reuptake inhibitors: such as dapoxetine, paroxetine, fluoxetine, etc., primary and secondary premature ejaculation with the drug can be obtained to a certain effect. However, the use of such drugs may cause nausea, headache, diarrhea, dizziness and other adverse reactions, and allergic to the drug should be prohibited. 2. Local anesthesia drugs: local anesthesia drugs can reduce penile sensitivity to improve the treatment of premature ejaculation, mainly a mixture of lidocaine and proparacaine, but the dosage of the drug will cause numbness of the head of the penis, and long-term use of the drug may cause a weakening of erectile function. Premature ejaculation patients can not self-abuse of drugs, medication should follow the doctor’s instructions.