Symptoms of advanced bladder tumor: 1. Cancer pain. As the tumor grows further and destroys the surrounding tissues, it can cause stubborn pain. The pain is progressively aggravated, which seriously affects the quality of life of patients and requires long-term reliance on pain medication to relieve the pain. 2. Persistent hematuria, which can occur when the cancer grows and damages the mucous membrane, causing the tumor tissue to break down and bleed. In severe cases, it may cause hemorrhagic anemia or hemorrhagic shock. When the tumor grows and causes urethral compression and bladder neck invasion, the patient will not be able to urinate and will experience painful urination and difficulty in urination. If necessary, long-term catheterization or cystostomy is needed. 4. Cachexia, tumor growth consumes normal human nutrients, resulting in a sharp decline in body mass, hypoproteinemia, muscle consumption, fat consumption, protein tissue consumption and skin and bones, immunity decline, fatigue and weakness, inability to get up, etc.