Anticoagulants, analgesics, or heart rate control medications can be used to regulate the discomfort of patients after aortic coarctation stenting. Aortic coarctation is a rare and dangerous disease, the main clinical manifestation of which is sudden chest, back and abdominal pain. Once diagnosed, it requires immediate surgical treatment, and the main mechanism of stenting is to separate the aneurysm from the blood flow, so as to allow the aneurysm to decrease in size and gradually eliminate itself. The main mechanism of stenting is to isolate the aneurysm from the blood flow and allow the aneurysm to diminish in size and gradually disappear. Anticoagulants, coumarins such as dicoumarin and warfarin, and antiplatelet agents such as aspirin, can be used to prevent thrombosis after stenting. Analgesic drugs can also be used after aortic coarctation stenting. Usually, the patients have obvious pain after the operation, and morphine drugs can be used to relieve the pain, and the patients’ vital signs should be closely observed while using analgesic drugs. Aortic coarctation patients may have increased blood pressure and heart rate, need to control the patient’s blood pressure and heart rate, can use beta-blockers such as metoprolol, esmolol and other drugs to lower blood pressure. It should be noted that the use of the above drugs should be under the supervision of a physician.