Flat warts are a benign growth caused by human papilloma virus (HPV) infection of the skin and mucous membranes. Flat warts on the neck can be removed by medication, surgery and physical therapy. 1. drug treatment: including local topical drugs and intramuscular injection of immune preparations. Topical ointments include salicylic acid ointment, 5% imiquimod ointment and fluorouracil ointment, which can relieve localized keratinized hyperplasia, but are prone to recurrence. Immune preparations include BCG polysaccharide ribonucleic acid injection and thymus peptide injection, which can regulate the immune level of the body and enhance the body’s ability to resist infection. 2. Surgical treatment: take the complete thin layer of warts on the neck, and then the warts will be deeply implanted in the body, stimulate the body to release cytokines, produce anti-virus antibodies to be able to remove the human papilloma virus on the epidermis, this method can also achieve the purpose of reducing the recurrence rate. 3. Physical therapy: including CO2 laser, microwave therapy and liquid nitrogen freezing methods, have a certain effect on the treatment of flat warts. The treatment process can be mild pain, for those who do not tolerate pain can be local anesthesia. It is recommended that people with flat warts go to a regular hospital, choose the right program under the guidance of the doctor, and actively treat it.