Premature ejaculation refers to a shortened ejaculatory latency, with ejaculation occurring at the onset of intercourse or even before intercourse. The causes of premature ejaculation may include psychological or mental factors, somatic diseases, etc. Common treatments include oral medications, psychological behavioral therapy, etc. There are many causes of premature ejaculation, commonly psychological and mental factors, hormonal disorders, prostatitis and so on. During sex, factors such as emotional tension and excitement and too much foreplay time may cause premature ejaculation. Hyperthyroidism in the body may also cause secondary premature ejaculation. Prostatitis may cause shortened ejaculatory latency due to excessive secretion of prostatic fluid. Premature ejaculation caused by psycho-spiritual factors is mostly treated with psycho-behavioral therapy. Through psychological and behavioral therapies, men are helped to develop sexual skills, increase sexual confidence and prolong ejaculation time. Premature ejaculation due to somatic diseases is mainly treated with medication. Dapoxetine is a common drug used to treat premature ejaculation, and common adverse effects include transient diarrhea, vomiting, and dizziness. Patients with premature ejaculation need to consult a doctor for examination and early treatment, and the drug should be applied under the guidance of a doctor.