You can take antipyretic medication when your body temperature rises, and a drop in temperature is usually accompanied by sweating. If there is sweating, then the body temperature will generally not continue to rise, and in most cases there will be a decrease in fever temperature. So if the fever doesn’t go down at this point, you can wait a little bit because the sweating is too short and the body temperature won’t come down so quickly yet. However, if you sweat for a while or even sweat profusely, but your temperature still does not go down when measured, it means that you do produce more heat and sweating does not cause your fever to go down. This is a good time to consider other causes, such as more unusual cases, like in heat stroke, also known as pyrexia, where insufficient heat dissipation can occur. In this case the patient is placed in an environment with more heat dissipation, and this is also the case when sweating does not reduce the fever. And in some cases where heat dissipation is sufficient, sweating does not reduce the fever, mainly because of increased heat production. This is when the inflammatory response is considered to be more pronounced and should be treated accordingly.