Moles on the mouth generally refer to pigmented nevi, which can be removed by laser treatment and surgery. Pigmented nevus is a localized skin change caused by benign proliferation of melanocytes, which can grow on face, neck, back, limbs, etc. Most of them are benign changes, and the degree of malignancy is relatively low. 1. Laser treatment: If the mole on the mouth is small, it can be removed by laser, such as CO₂ laser, etc. After the operation, it is necessary to keep the wound dry and clean, and if accompanied by bacterial infection, it can be treated with topical mupirocin ointment. This treatment method has the possibility of recurrence. 2. Surgery: If the mole on the mouth is relatively large, or local redness, swelling, ulceration, pus, etc., you can directly use traditional surgical excision, and send the cut tissues to pathological examination to clarify the nature. Cosmetic suture should be chosen during the surgery, and attention should be paid to keep the local area dry and clean after the surgery to prevent infection and reduce the formation of scar. If the mole on the mouth is small, it can also be necrotic by applying liquid nitrogen freezing to make the local proliferation of melanocytes. However, because the area and depth of removal are not easy to grasp, easy to cause scarring, and there is also the possibility of recurrence, so clinically this method is no longer recommended for use. It is recommended that patients with moles on the mouth should go to a regular hospital in time and choose the appropriate treatment under the guidance of the doctor.