Panic heartbeat after taking nicorandil is related to the drug’s vasodilatation, which is an adverse reaction of the drug. Nicorandil has the effect of vasodilatation, especially for coronary artery dilation is more obvious, clinically can be used for angina pectoris, coronary heart disease treatment. Some patients are more sensitive to the drug, after taking the drug appeared peripheral vasodilatation, there may be a certain degree of blood pressure reduction, at the same time reflexive heart rate acceleration, manifested as palpitations, panic. Some patients may also experience adverse reactions such as headache and head swelling. Patients with glaucoma, severe liver or renal insufficiency should not use this drug. The use of medication should consult a professional physician, and if there are any uncomfortable symptoms in the process of taking medication, it is necessary to go to the hospital in a timely manner, and can be treated under the guidance of a physician.