Oshitinib has skin, digestive system, respiratory system, cardiovascular system related side effects; patients with side effects should be treated symptomatically according to the situation, and the dosage should be reduced or even stopped if necessary. 1. Skin: OXITINI can cause herpetic dermatosis, and the symptoms can be rapidly improved after stopping the drug and giving corticosteroid drugs, such as hydrocortisone. In addition to this, OXITINI can also cause generalized darkening of the skin, as well as symptoms such as itching, pain and cracking of the skin of the fingers; 2、Digestive system: OXITINI can cause oral ulcers, decreased appetite, abdominal pain, diarrhea, bloody stools, constipation, liver function abnormalities and other digestive symptoms and damage, so during treatment patients should avoid caffeine, alcohol, dairy products and spicy foods, need to eat small meals, monitor liver function; 3, respiratory system: interstitial lung disease and pneumonia is a common complication after the use of OXITINI, general patients in the use of corticosteroids such as prednisone treatment, re-administration of the drug after the side effects are less. If interstitial lung disease is diagnosed after administration, it should be permanently discontinued and necessary therapeutic measures should be taken; 4, cardiovascular system: patients at risk of QT interval prolongation need to undergo electrocardiographic testing when using this drug, and beta-blockers such as metoprolol should be given for treatment after occurrence. If the patient has a combination of serious arrhythmias such as tip-twisting ventricular tachycardia and polymorphic ventricular tachycardia, permanent discontinuation of the drug should be considered. Medications should be used under medical supervision.