Overindulgence can lead to premature ejaculation in men. Premature ejaculation is a common sexual dysfunction disease, and the dividing line that leads to overindulgence is not the same due to the different physique of each person. Men may cause repeated congestion of the reproductive organs due to frequent sexual intercourse, and the sexual nerves become sensitive thus causing premature ejaculation; it may also cause inflammation of the prostate gland, accompanied by premature ejaculation. If premature ejaculation occurs, it is recommended that the patient should exercise moderation in sexual life and pay attention to physical exercise. At the same time also in the doctor’s advice to use dapoxetine, paroxetine and other drugs for treatment. Over-indulgence can lead to premature ejaculation, patients are advised to avoid over-exertion and not to have sex too often in daily life. Dietary attention to nutritional balance, daily attention to strengthen exercise, enhance physical fitness.