How should mumps be prevented? Quarantine patients early until the mumps have completely subsided. Contacts are generally not necessarily quarantined, but in collective children’s institutions (including hospitals and schools), troops, etc. should be retained for 3 weeks, and suspected patients should be immediately and temporarily isolated. Live attenuated mumps vaccine: Live attenuated vaccine in chicken embryo cell culture, which has been used in large quantities abroad since 1966, is effective in preventing infection in children up to 97% and in adults up to 93%, and the combination of live mumps vaccine with measles and rubella vaccines at the same time gives satisfactory results without interference between the three. Neutralizing antibodies to mumps virus can be maintained for at least 9.5 years after immunization. In addition to intradermal and subcutaneous injections, the immunization route of the live mumps vaccine is also effective by nasal spray or aerosol inhalation (performed in an aerosol chamber). Our material proves that six months after immunization (nasal spray and aerosol inhalation combined), the morbidity rate of the child immunization group (7.4%) was significantly lower than that of the corresponding control group (78.5%), and the morbidity rate of the adult immunization group (0.33%) was also lower than that of the corresponding control group (4.6%), and there were no adverse reactions. In view of the high incidence and severity of the disease in China, the use of mumps vaccine (including adults) should be arranged in a planned manner. Especially for new kindergarten classes, universal immunization can significantly reduce the incidence of the disease. The use of this vaccine has been gradually promoted in China. The live mumps vaccine should not be used in pregnant women (in order to prevent the virus from infecting the fetus via the placenta with adverse consequences), in people with congenital or acquired immune deficiency, and in people who are allergic to egg proteins (because the live vaccine is obtained from chicken embryos). General immunoglobulins, adult blood or placental globulins have no preventive effect against the disease. Blood of recovered patients and their immunoglobulins or specific high-valent immunoglobulins may be useful, but the source is difficult and not easy to obtain, and the protection time after use is short, only 2-3 weeks, so it is not used much, and its effect is yet to be further studied.