Itching on both sides of the cheeks and chin, usually accompanied by rash and erythema, may be the occurrence of contact dermatitis, eczema, acne, folliculitis, etc. 1, contact dermatitis: patients may mistakenly use cosmetics, mainly manifested as erythema, papules, blisters, conscious itching of the skin, can be manifested in the cheeks and chin, if blisters exist, should not be scratched frequently, blisters rupture and ooze, skin wound moist, easy to infect, to avoid Eczema: Erythema, papules, papules, blisters, vesicles, oozing, crusting, scaling and other manifestations can be seen, the cause is complex and caused by a variety of internal and external factors. It is mainly related to abnormal androgen levels, sebum secretion, abnormal keratinization of cells around the hair follicle and inflammatory reactions, mainly caused by Propionibacterium acnes. You can apply local medication to inhibit sebaceous gland secretion and the growth of P. acnes, combine with isotretinoin soft capsules, and take oral levocetirizine hydrochloride to enhance anti-itch; 4. Folliculitis: such as Malassezia folliculitis, which can be very similar to acne in performance and caused by Malassezia infection, can be diagnosed by fungal microscopy, and apply oral and topical antifungal medication; 5. Other: dry skin, low sebum secretion, flaking In addition, very low environmental humidity can make the skin itchy, attention should be paid to hydration, unreasonable skin care, exposure to ultraviolet radiation and other causes of skin barrier damage, the skin can show red and itchy symptoms, should be under the guidance of a doctor to choose the appropriate medication to repair the skin barrier.