High-risk HPV infection is clinically possible if you are pregnant, but it is important to note that persistent high-risk HPV infection can clinically lead to cervical precancerous lesions and even cervical cancer, so colposcopy is recommended to find out whether the cervical epithelium is diseased. It is advisable to be hospitalized for observation during colposcopy, because colposcopy requires cervical biopsy for pathology, as stimulation may cause abruption between the gestational sac and the uterine wall, resulting in the clinical possibility of pre-eclampsia or spontaneous abortion. Progesterone is used to inhibit the contraction of the smooth muscle of the uterus to avoid the possibility of preterm or inevitable miscarriage.