What are the medication reminders for pregnancy with mental disorders?

For the safety of the child, it is best to discontinue all medications during the first trimester of pregnancy to avoid fetal malformations and impact on fetal development. However, it is often human for patients and their families to want to have their own children. Discontinuing medication can easily lead to a relapse of the disease, and the two are in conflict. The FDA classifies drugs into five categories based on their effect on the fetus: Pregnancy A A sufficient number of well-controlled human studies have shown no adverse effects on the fetus in early pregnancy (and no such signs in late pregnancy). Pregnancy B Animal studies have failed to show an adverse effect on the embryo, but there is a lack of sufficient number of well-controlled human studies to confirm this; or Animal studies have shown a possible adverse effect on the embryo, but sufficient number of well-controlled human studies have shown no adverse effect on the fetus during pregnancy. Pregnancy C Animal studies have shown that the drug may have adverse effects on the embryo, but there is a lack of sufficient number of well-controlled human studies to confirm this; however, due to therapeutic needs, the drug should be used in pregnant women on balance, even if there is a potential for such effects. Pregnancy D The drug is known to be potentially harmful to the fetus from ‘adverse reaction’ information obtained from market research or information feedback, or from human studies; however, due to therapeutic needs, the drug should be used in pregnant women even if there is such potential, on balance. Pregnancy X Where the drug has been shown to cause embryonic malformations from animal or human studies and/or ‘adverse reaction’ information from market research or feedback, or from human studies, and the drug is known to be potentially harmful to the fetus, it is clear on balance that the drug should not be used in pregnant women, even if required for therapeutic reasons. The drug should not be used in pregnant women, even if it is necessary for treatment. Trazodone, mianserin, mirtazapine, fluoxetine, sertraline are pregnancy C; bupropion, maprotiline for pregnancy B (3) anti-anxiety (sleeping) drugs and new anti-anxiety drugs: benzodiazepines (Valium a class) such as alprazolam, clonazepam, lorazepam, diazepam, midazolam, zopiclone, etc., are pregnancy D, triazolam, estradiolam for pregnancy X, should be prohibited. Zolpidem (Synthroid), bupropion copper, for pregnancy B; (4) Mood stabilizers: lithium carbonate, carbamazepine, valproate, for pregnancy D, should be prohibited. Lamotrigine and gabapentin are pregnancy C; (5) Treatment of memory disorders and anti-dementia drugs: Analgin, Donepezil and Esnon, all pregnancy C. Referring to the opinion of Professor Yan Wenwei, a highly respected mental health expert in China and the Shanghai Mental Health Center, according to the opinions of experts at home and abroad, if pregnancy occurs when suffering from mental illness, the following can be implemented: (1) When pregnant, it is perfectly acceptable to use antipsychotics ( amisulpride, sulpiride not known) or antidepressants (minus methylphenidate, paroxetine, promethazine, mipramine, paroxetine), generally speaking, there is no teratogenic problem. (2) The general anti-anxiety (sleeping) drugs of the Valium class are teratogenic and should be prohibited. Zolpidem (Synthroid) and butalbital copper can be used. (3) Lithium carbonate, carbamazepine, valproate have teratogenic potential and should be prohibited. Or may be replaced with lamotrigine, gabapentin. Special reminder: For all medication use, consultation with a psychiatrist is required, as all medication classifications require the guidance of a psychiatrist. If taking medication, it is recommended to have more prenatal checkups such as 3D ultrasound, 4D ultrasound, amniotic fluid examination to see if the fetus has any limb malformation, heart malformation, spina bifida, etc. to prevent accidents, remember. Special reminder: Do not breastfeed if you are taking medication while breastfeeding and your milk contains medication to avoid affecting your infant’s development. Whether or not a child will inherit a mental illness is completely unrelated to taking medication. There is a 1% chance that a child will develop a psychiatric disorder if the parent does not have schizophrenia. If one parent has the disorder, the likelihood is 5-10 times greater. 90% are likely to be fine. And even if the gene for the disease is inherited, it doesn’t necessarily develop; if it does, it will be a decade or so later. By that time, science will be more advanced and treatment methods may be very advanced. However, in the end, the choice of how to choose and how to have a child is ultimately at the discretion of the patient and family, and the decision rests with the patient and family.