HPV type 52 positive is not necessarily found to progress to cervical cancer; only a small percentage of patients may develop cancer after several years or even a dozen years without treatment. HPV virus, also known as human papillomavirus, mainly infects female cervical squamous epithelial cells and can be divided into two types: high-risk and low-risk, with HPV type 52 being the high-risk HPV virus. If the cervix is stimulated by high-risk HPV for a long time, there is a real risk of cancer, and it takes a long time to cause such pathological changes, up to several years or even ten years. In addition, some low-risk HPV viruses may disappear on their own as the cancer-causing factors disappear. Therefore, there is no accurate data to determine how long it takes for HPV infection type 52 to progress to cervical cancer, and it needs to be judged in the context of the patient’s own condition and treatment effect. It is recommended that women should have cervical HPV examination and TCT examination once every two years to clarify whether there are cervical intraepithelial lesions and high-risk factors triggering cervical cancer, so as to provide timely intervention and avoid further development of the disease.