The 41-year-old Zhang had a hysterectomy for multiple fibroids and had hot flashes for more than a month after the operation, why? The hysterectomy can affect the balance and stability of the human endocrine environment and lead to a series of menopausal symptoms such as lipid metabolism disorder and premature ovarian failure. Hysterectomy can affect the blood flow to the ovaries, accelerate the process of ovarian failure, and decrease estrogen secretion, increasing the risk of coronary heart disease and osteoporosis, even if unilateral or bilateral ovaries are preserved. Therefore, hysterectomy should be approached with caution, and should not be done casually unless there is a malignant disease or a disease that cannot be resolved by hysterectomy.