Endoscopic retrograde cholangiopancreatography (ERCP) under pancreatic bile duct lithotripsy can remove common bile duct stones without opening the abdomen, and has accurate diagnosis and high treatment success rate; no body surface wound, light physiological interference, and little pain for patients; high safety, eliminating lesions and leaving no traces; quick recovery, and can be discharged in three to five days after surgery under smooth conditions; fast results, repeatability, and few complications. Nearly 100 cases of stone extraction have been successfully carried out, enabling patients to avoid the pain and complications of open surgery, rapidly relieving symptoms and shortening hospitalization time, greatly reducing the patient’s pain and economic burden. Due to the poor lifestyle habits of modern people: preferring to be quiet and less active, skipping breakfast and snacking after meals, etc., they are prone to gallstones. If gallstones are not treated or postponed for fear of surgery, it will gradually induce a variety of syndromes, resulting in “small diseases becoming big diseases” and even life-threatening. Therefore, once gallstones are detected, they should be treated in a timely manner. Transendoscopic retrograde cholangiopancreatography (ERCP) is to insert an electronic duodenoscope into the descending duodenum, find the duodenal papilla, insert a plastic catheter into the biopsy duct to the opening, inject a contrast agent and take an X-ray to show the pancreaticobiliary duct, which is currently recognized as the best means to treat pancreaticobiliary duct diseases. On the other hand, the endoscopic retrograde cholangiopancreatic cholangiopancreatic lithotomy is based on the endoscopic implementation of duodenal papillary sphincter dissection and careful removal of bile duct stones with a balloon or lithotripsy (lithotripsy) mesh basket. The whole procedure is less painful for the patient and less physiologically disturbing. Endoscopic duodenal sphincterotomy is risky, difficult, and technically demanding, and requires not only the appropriate surgical equipment, but also a specially trained surgeon. Our doctors have been trained in famous hospitals in China and have systematically learned the implementation of various interventional procedures under endoscopic retrograde cholangiopancreatography, and have strong operational skills and clinical experience, which reduces the risk of endoscopic duodenal sphincterotomy and greatly ensures the success rate of stone extraction and surgical safety.