The cause of trigeminal neuralgia is vascular compression, and the only way to remove the cause is to open the skull to isolate the blood vessels without compression. Craniotomy can remove the root of the problem, but there are some risks. Drugs can be used carbamazepine, which is cheaper. However, there will be liver and bone marrow damage for a long time. Internationally, it is advocated to use radiofrequency thermal coagulation of ganglion to block neuralgia without medication or surgery, and the operation requires accurate injection under X-ray guidance, which is very safe. The analgesic effect is exact, more than 95% of excellent analgesia, after the injection will feel some numbness of the skin, the appearance can not be seen, about 3-5 years relapse need to be injected again. Radiofrequency treatment in our department is generally hospitalized for the whole process is about 8000 yuan, we commonly use the degree of damage is to feel the skin wooden, there is a sense of touch and taste, the quality of life affects less. Several years later the nerve will grow again will and pain recurrence, 3-5 years after the recurrence of another injection. But nerve destruction is very strong completely no skin perception of the elderly some can maintain more than 15 years. Gamma knife or cytoknife treatment is to destroy the nerve with radiation, which is also sure to recur, and the effect is slower. Some of them have pain relief only after six months, and because the branches of the nerve cannot be identified during the operation, there will be numbness all over.