The main clinical symptoms of novel coronavirus infection are dry cough, fever, malaise, chest tightness, shortness of breath, and even difficulty in breathing. However, it is important to note that if the patient has a mixed infection with other pathogens, such as bacterial or fungal pneumonia, the patient’s cough can be significantly increased and purulent sputum can be coughed up, and some patients can also have blood in the sputum. Therefore, for patients with novel coronavirus pneumonia, when coughing up sputum, especially purulent sputum, it is necessary to pay attention to the early review of sputum culture, sputum fungal smear, sputum tuberculosis smear, blood count, calcitoninogen, and review of lung CT and other tests to clarify whether there are other secondary infections, and if necessary, add symptomatic treatment with sensitive anti-infective drugs.