Bedwetting at the age of 12 may be normal if it occurs occasionally. Long-term bedwetting can be considered as pediatric enuresis, urinary tract infection or neurogenic bladder, and it is recommended to seek timely medical treatment. Common causes 1. Normal condition: children do not develop good urination habits or are overexcited before bedtime, the cerebral cortex is in the excitement stage, the nerves are stimulated and bedwetting easily occurs; 2. Pediatric enuresis: may be caused by genetic factors, delayed development of the cerebral cortex, resulting in contraction of the detrusor muscle, accompanied by symptoms such as frequent and urgent urination; 3. Urinary tract infection: mostly caused by bacterial infections, such as Escherichia coli, mainly manifested for urinary frequency, urinary urgency, urinary pain, which can develop into urinary incontinence; 4, neurogenic bladder: a variety of diseases leading to urinary storage and voiding neuromodulation dysfunction, such as intervertebral disc lesions, which can lead to urinary retention and painful urinary symptoms. Treatment 1, urination training: increase the time between urination and expand the bladder volume. Regular urination before bedtime, interrupt for ten seconds when urinating and then urinate to improve the bladder sphincter ability; 2, medication: it is recommended to use medication under the guidance of a doctor, nocturnal polyuria can use desmopressin to improve the symptoms of enuresis, urinary tract infection can be treated with anti-infective treatment such as amoxicillin clavulanic acid potassium, cefaclor, etc.; 3, other methods: such as transcutaneous electrical nerve stimulation, acupuncture, massage, etc., need to be operated by a professional doctor. Precautions 1, daily attention to personal hygiene, diligent change of underwear, do not wear tight pants; 2, parents should help their children to build self-confidence and develop good urination habits.