It is usually considered that obvious jaundice with a total serum bilirubin greater than 34µmol/L is contraindicated for intervention. However, if the patient is combined with obstructive jaundice, the tumor is single, well-defined, and located in the hilar region compressing the intrahepatic bile duct, while the intrahepatic bile duct is not yet significantly dilated. In this case, we can still consider hepatocellular carcinoma intervention first, and monitor the dilatation of intrahepatic bile ducts with ultrasound after intervention, and then perform PTCD in time once the dilatation is obvious; if there is obvious dilatation of intrahepatic bile ducts at the beginning, PTCD should be performed first, and then perform hepatocellular carcinoma intervention when the jaundice decreases slightly. If the patient is combined with hepatocellular jaundice (i.e. poor liver function itself) and the tumor is diffuse, intervention should not be performed.